Reproduction
Object numberRCSHC/P 268
Scientific nameHomo sapiens
CollectionHunterian
CategoryWet preparations
Object nameIleum, Typhoid fever, Affections of the Peyer's Glands, Mounted wet tissue
DescriptionPortion of ileum showing two collections of Peyer's glands exhibiting the pathological changes consistent with typhoid fever.
The injected blood vessels provide clear identification of the inflamed, but less vascular, lymph glands, showing their bordered elevation from the surrounding tissue and their ulcerated surfaces.
Production date 1763 - 1764
Preparator
Owner/user
Surgeon/clinician
Associated institution
presented
Physical Location
LocationOn display in the Hunterian Museum, Room 4: The Long Gallery
Physical Information
Physical descriptionWet preparation of tissue mounted in a cuboid perspex container.
Materialperspex, Kaiserling III
Dimensions
whole height: 115 mm
whole width: 86 mm
whole depth: 53 mm
whole weight: 586 g
whole width: 86 mm
whole depth: 53 mm
whole weight: 586 g
Bibliography
SourceProger 1966-1972
Vol. 1, page 182.
NotesText taken from Stanley & Paget (1846-9), and Paget (1882-5).
TranscriptPortion of ileum of which the blood-vessels were minutely injected. Two collections of Peyer's glands are elevated above the surrounding membrane, and their surfaces are rendered irregular by numerous long and chiefly transverse ulcerated (?) depressions. Adjacent to them are several small circular ulcers with elevated round margins. The parts occupied by the glands are much less vascular than those around them.
The preparation is engraved in Baillie's Morbid Anatomy, Fasc. iv, Pl. 2, fig 3. The specimen is probably a part of that which Mr Hunter describes in the following case:
SourceHunter Casebooks
Dissections of Morbid Bodies, No. 68, pages 321-2.
NotesAlso in Proger 1966-72.
TranscriptWinter 1763/4. A man in Mr Fordyce's Hospital had just recovered of a Fever, when he was taken ill with a violent pain in his Belly just at the Navel. He was ordered a Clyster, and a Blister; but he had a natural stool; the pain continued, and within twenty hours of the attack he died. Upon opening the Belly we found the Peritonaeum very much inflamed: the Epiploon covered with whole [of the] Viscera, and was of a darkish colour, as if wetted with blood. We found an universal inflammation in the whole visible contents of the Abdomen: The Liver was glued to the Diaphragm and the Stomach, where-ever it touched. All the intestines were likewise glued together, and of a very dark colour where there was no compression by other Surfaces. I examined the gall-bladder, and found it as large as my fist, and two holes at its fundus. Upon introducing my finger I found two more. There was very little Bile in it, for it had all got loose in the cavity of the abdomen, and had by that [means] tinged the Glutine. I took out a piece of the Ileum to inject, to see the size of the Vessels; which I did. Upon the inside of the intestines I observed several bodies some as broad as a farthing, some smaller: they had a depression in their middles, so that they appeared like circular or oval ridges or risings. The texture of these risings were spongy or cellular, whose openings loosed into the Guts. Some of them appeared to be a thickening of the Rugae of the internal surface; for in the oval ones I could trace two rugae into them. Why they should be depressed in the middle, I can't tell; but this appearance I have often seen. Was the Gall-bladder become rotten in this short time, or was it just burst as the pain came on, and was the cause of this universal inflammation in the abdomen? This is somewhat reasonable; as the inflammation seemed to be more on the external surface of the Viscera than on the internal.
SourceClift 1830 Part 1
NotesCatalogue number 820
TranscriptA portion of small intestine [the ilium] showing several small ulcers in the glandulæ aggregatæ. The intestine is injected.
