Reproduction
Object numberRCSHC/P 97
Scientific nameHomo sapiens
CollectionHunterian
CategoryWet preparations
Object nameColon, Amebiasis, Ulcer, Ulceration & Suppuration, Mounted wet tissue
DescriptionPortion of the colon showing numerous round and oval ulcers in the mucous membrane.
The amoebic ulcers are clearly and regularly defined in the tissue, many forming a conical shape, with wider bases than apertures, undermining the mucous membrane. Some ulcers appear to have granulated, secretion covered bases. The ulcers are typically placed transversely to the axis of the intestine.
The patient in this case was Admiral Augustus John Hervey, third earl of Bristol (1724-1779), who was afflicted with 'gout of the stomach' during his later years.
Production date 1779
Preparator
Owner/user
Patient/subject
presented
Physical Location
LocationOn display in the Hunterian Museum, Room 4: The Long Gallery
Physical Information
Physical descriptionWet preparation of tissue mounted in an oval glass jar with glass lid.
Materialglass (material)
Dimensions
whole height: 117 mm
whole width: 90 mm
whole depth: 50 mm
whole weight: 544 g
whole width: 90 mm
whole depth: 50 mm
whole weight: 544 g
Bibliography
SourceProger 1966-1972
Vol. 1, page 47.
NotesText taken from Stanley & Paget (1846-9), and Paget (1882-5).
TranscriptPortion of the colon, in the mucous membrane of which are numerous round and oval ulcers, from one to three lines in diameter. The long axis of the oval ulcers are placed transversely to the axis of the intestine. Their margins are thin, clean, and regularly defined, and in several instances project over their bases, which are generally more widely ulcerated, and are like the cavities of small cup-shaped open abscesses in the submucous tissue. The bases of some of the ulcers appear granular, and are covered with secretion. The intervening portions of the mucous membrane, and the other adjacent tissues, appear healthy.
SourceHunter Casebooks
Dissections of Morbid Bodies, No. 174, page 392-3
NotesThe appearances upon Opening the Body of the Right Hon.ble [sic.] The Earl of Bristol. (Also in Proger 1966-72.)
TranscriptOn opening the Chest, the cartilages of the ribs were found ossified. The first thing that presented itself was more fat than common upon the Pericardium. Upon opening this Membrane I found that it adhered every where to the heart. The heart was so remarkably small that I could not help wondering at it; but it was sound in its substance. Was this owing to the pericardium's adhering to it? - The diaphragm was remarkably high, so as to make the chest very short, between the upper and lower part; yet the lungs were perfectly sound, and free from adhesions.
The liver was small , and much more in the right side than common, so much so, that the gall-bladder was quite in the right side, and the ligamentum rotundum almost in the right. Some adhesions to the diaphragm of old standing on the upper surface; but on the whole pretty sound. The gall-bladder was very small, containing no bile; but a transparent slimy mucus. A small gall-stone lay in the beginning of its duct, which obstructed the passage of the bile into it. This would hint as if the gall- bladder did not secrete bile.
The hepatic ducts, and ductus communis were perfectly free, and the bile in them was of a light yellow colour. The stomach contained a dark coloured liquor, which was continued through the whole of the small intestines, but rather becoming yellower towards the last. The stomach did not appear unsound.
The duodenum, jejunum, and most part of the ilium were sound, but the ilium towards the last was a little ulcerated. The colon and rectum on their inner membrane, were ulcerated in a great number of places, through their whole lengths; and in some of these ulcerations there were evidently steaks of blood. They contained some yellow faeces with a great deal of slimy mucus. The pancreas was sound. The Bladder was sound. The external appearance of the Stomach and intestines was rather darker than common; in other respects they appeared very sound. The darkness of the colour of the contents of these canals was most probably owing to an extravasation of blood in the Stomach, although I could not observe from whence it came: but I believe it may be remarked, in general, that a small extravasation of blood in the stomach soon loses the blood tinge, and becomes livid.
When this inky-coloured Coffee was diluted, it did not give the least tinge of blood or bile; therefore if it was either the one or the other, it had then lost these qualities by the power of the Stomach. If it was the bile, there was no reason to suppose it to be of this kind when secreted, as the bile in the Ducts was yellow, or of a natural colour: and what is next to a proof of this [is], the faeces gave a yellow tinge when diluted, which they would not have done, if this in the Stomach had been the Bile.
He had been long affected with the Gout before his Death, and of which he died. He had frequent vomitings of this black fluid, which was called Black Bile: he had also a purging, with blood. At last he had Hiccough, and died.
SourceClift 1830 Part 1
NotesCatalogue number 843
TranscriptA portion of the colon of a nobleman, with numerous ulcerations on its internal surface.
SourceClift 1830-1831
TranscriptVide Dissectio 174. page 282.
